Rivaroxaban okayed for PE in Europe

But the combination of phentermine and topiramate was not recommended for approval for the treatment of obesity because of concerns about long-term side effects.

via The Heart

Look AHEAD Trial Halted

Look AHEAD, a large cardiovascular-outcomes study that included 5145 adults with diabetes and a body-mass index >25 kg/m2, failed to show a difference in the rate of nonfatal MI, nonfatal stroke, death, or hospitalization for angina among patients randomized to an intensive lifestyle intervention and those randomized to a control arm consisting of education alone.

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via Medscape news

Look AHEAD halted: Lifestyle management fails to reduce hard outcomes in diabetics

Look AHEAD, a large cardiovascular-outcomes study that included 5145 adults with diabetes and a body-mass index >25 kg/m², failed to show a difference in the rate of nonfatal MI, nonfatal stroke, death, or hospitalization for angina among patients randomized to an intensive lifestyle intervention and those randomized to a control arm consisting of education alone.

via The Heart

Wider fibrate use urged in mild to moderate CKD

Fibrates improve lipid profiles and reduce cardiovascular events and CV deaths in those with mild to moderate chronic kidney disease, according to a new meta-analysis. The authors are urging broader use of these agents in kidney patients.

via The Heart

Small increased risk of CV events with diclofenac

The European Medicines Agency has concluded in a new review that the NSAID diclofenac has a small but consistent increased risk of cardiovascular side effects compared with other NSAIDs. It has ordered a risk assessment on the agent to consider updating treatment advice.

via The Heart

Robotic-Assisted Cardiac Stent System Enhances Control And Improves Visualization

Innovative System a Big Leap Forward for Patients and Physicians Alike Thousands of cardiac stent procedures are successfully performed every year, but a key challenge is positioning the stent, guidewires, and catheter at the precise location of the blockage...

via Medical News Today

New anticoagulants beat warfarin in AF meta-analysis

The benefits of the new wave of anticoagulants for atrial-fibrillation patients are supported by a major meta-analysis of studies comparing the new drugs with warfarin.

via The Heart

FDA advisors vote 9 to 6 to approve mipomersen for homozygous FH

The vote came down to a balance over the relative risks and safety of drug, with some panelists not thrilled about the modest reduction of LDL-cholesterol levels and the increased risk of liver disease. In the end, though, they felt that this patient population needs all the help they can get in lowering their risk of cardiovascular events.

via The Heart

Second Erasmus probe finds scientific misconduct by Poldermans

A second investigation into research led by cardiovascular researcher Dr Don Poldermans has found that violation of academic integrity occurred. Poldermans denies any serious wrongdoing and calls the report a "witch hunt."

via The Heart